. Prostate cancer is the fourth most common cancer diagnosis in worldwide, with 1 300 000 new cases and 360 000 deaths in 2018 (Globocan 2018).
. At the initial diagnosis the disease, more than 60% of cases are diagnosed as localized prostate cancer.
. Localized prostate cancer can be asymptomatic at the early stage and often has an indolent course that may require only active surveillance.
. Indolent or aggressive, to treat or not to treat this cancer? This is always the question urologists ask themselves.